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Table 5 Different SIL groups display changes in microenvironment factors

From: Reconnoitering correlation between human papillomavirus infection-induced vaginal microecological abnormality and squamous intraepithelial lesion (SIL) progression

Variables

NILM (nā€‰=ā€‰317)

LSIL (nā€‰=ā€‰41)

HSIL (nā€‰=ā€‰25)

P

pH

Normal

26 (8.2)

4 (9.75)

2 (8.0)

0.226

Abnormal

291 (91.8)

35 (85.36)

23 (92.0)

Ā 

Microbiome density

Normal

199 (62.78)

19 (46.34)

8 (32.0)

<ā€‰0.001

Abnormal

118 (37.22)

25 (53.66)

17 (68.0)

Ā 

Microbiome diversity

Normal

182 (57.41)

22 (53.66)

10 (40.0)

0.035

Abnormal

135 (42.59)

19 (46.34)

15 (60.0)

Ā 

BV

Positive

165 (52.05)

18 (43.9)

17 (64.0)

0.037

Negative

152 (47.95)

23 (56.1)

8 (36.0)

Ā 

AV

Positive

151 (47.63)

19 (46.33)

15 (60.0)

0.029

Negative

166 (52.37)

22 (53.67)

10 (40.0)

Ā 

VVC

Positive

135 (42.59)

18 (43.9)

13 (52.0)

0.046

Negative

182 (57.41)

23 (56.1)

12 (48.0)

Ā 

TV

Positive

114 (35.96)

17 (41.46)

14 (56.0)

0.021

Negative

203 (64.04)

24 (58.54)

11 (44.0)

Ā 

CV

Positive

120 (37.85)

13 (31.7)

12 (48.0)

0.045

Negative

197 (62.15)

28 (68.3)

13 (52.0)

Ā 

Leukocyte esterase

Positive

250 (78.86)

34 (82.91)

22 (88.0)

0.039

Negative

67 (21.14)

7 (17.09)

3 (12.0)

Ā 

Sialidase

Positive

1 (0.32)

2 (4.88)

3 (12.0)

<ā€‰0.001

Negative

316 (99.68)

39 (95.12)

22 (88.0)

Ā 

Catalase

Positive

182 (57.41)

20 (48.78)

19 (76.0)

<ā€‰0.001

Negative

125 (42.59)

21 (51.22)

6 (34.0)

Ā 

Lactobacillus

Positive

145 (45.74)

18 (43.9)

17 (68.0)

<ā€‰0.001

Negative

172 (54.26)

23 (56.1)

8 (32.0)

Ā