Characteristic | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | |
Age, years | 0.082 | |||
<60 | Reference | |||
≥60 | 2.272 (0.902–5.721) | |||
BMI, kg/m2 | 0.039 | 0.052 | ||
<25 | Reference | Reference | ||
≥25 | 2.569 (1.048–6.297) | 3.078 (0.991–9.562) | ||
FIGO stage | 0.105 | |||
IA2-IB1 | Reference | |||
IB2-IIA1 | 2.078 (0.859–5.029) | |||
Histological type | 0.476 | |||
SCC | Reference | |||
Non-SCC | 1.406 (0.550–3.593) | |||
Tumor size, mm | 0.015 | 0.506 | ||
<20 | Reference | Reference | ||
≥20 | 2.829 (1.226–6.527) | 1.411 (0.511–3.894) | ||
Depth of stromal invasion | 0.432 | |||
≤1/2 | Reference | |||
>1/2 | 1.392 (0.610–3.177) | |||
Lymphovascular space invasion | 0.802 | |||
No | Reference | |||
Yes | 1.159 (0.366–3.671) | |||
Lymph node metastasis | 0.066 | |||
No | Reference | |||
Yes | 3.312 (0.926–11.850) | |||
iAE | < 0.001 | < 0.001 | ||
No | Reference | Reference | ||
Yes | 19.885 (7.352–53.778) | 15.100 (4.735–48.158) | ||
OSATS score | 0.579 (0.437–0.767) | < 0.001 | 0.860 (0.619–1.194) | 0.367 |