Table 2 Univariate and multivariate analyses of risk factors for recurrence-free survival

Age

0.621

 ≤ 40

1.38

0.61–3.13

0.442

 40–60

0.99

0.52–1.91

0.986

 > 60

1[Reference]

Vaginal invasion

 Yes

1.48

0.89–2.47

0.134

 No

1[Reference]

FIGO Stage

< 0.001

 I

0.27

0.12–0.58

< 0.001

 II

0.46

0.25–0.84

0.012

 III C

1[Reference]

Parametrial invasion

 Pos

4.62

2.56–8.33

< 0.001

3.19

1.74–5.85

< 0.001

 Neg

1[Reference]

Surgical margin

 Pos

3.23

1.53–6.82

0.002

 Neg

1[Reference]

No. of LN+

< 0.001

1.99

1.46–2.71

< 0.001

 ≥ 3

4.32

2.35–7.96

< 0.001

3.96

2.12–7.36

< 0.001

 1–2

1.95

1.05–3.62

0.034

1.98

1.06–3.72

0.032

 0

1[Reference]

1[Reference]

Depth of stromal invasion

0.081

 Deep 1/3

2.29

0.97–5.37

0.058

 Middle 1/3

1.37

0.50–3.76

0.544

 Superficial 1/3

1[Reference]

Tumor diameter

 > 4

3.42

2.00-5.86

< 0.001

3.24

1.89–5.54

< 0.001

 ≤ 4

1[Reference]

LVSI

 Pos

1.47

0.85–2.54

0.169

 Neg

1[Reference]

Nerve invasion

 Pos

1.44

0.73–2.85

0.291

 Neg

1[Reference]

Histological type

 SCC

0.62

0.33–1.18

0.145

 Non-SCC

1[Reference]