Table 3 Univariate and multivariate analyses of risk factors for recurrence-free survival in LNM group

Age

0.848

 ≤ 40

26(20.6)

8(30.8)

0.83

0.25–2.76

0.765

 40–60

77(61.1)

22(28.6)

0.75

0.28–2.02

0.569

 > 60

23(18.3)

8(34.8)

1[Reference]

FIGO stage

 III C2

23(18.3)

13(56.5)

4.06

1.59–10.38

0.003

 III C1

103(81.7)

25(24.3)

1[Reference]

Parametrial invasion

 Pos

17(13.5)

12(70.6)

7.66

2.47–23.78

< 0.001

3.51

1.76-7.00

< 0.001

 Neg

109(86.5)

26(23.9)

1[Reference]

Positive vaginal margin

 Pos

8(6.3)

5(62.5)

4.29

0.97–18.99

0.055

 Neg

118(93.7)

33(28.0)

1[Reference]

No. of LN+

0.007

 ≥ 3

44(34.9)

20(45.5)

2.96

1.34–6.54

1.94

1.02–3.69

0.043

 1–2

82(65.1)

18(22.0)

1[Reference]

Depth of stromal invasion

0.053

 Deep 1/3

83(65.9)

31(37.3)

10.14

1.29–79.93

0.028

 Middle 1/3

25(19.8)

6(24.0)

5.37

0.59–49.22

0.137

 Superficial 1/3

18(14.3)

1(5.6)

1[Reference]

Tumor diameter

 > 4

53(42.1)

25(56.6)

4.12

1.84–9.23

0.001

2.95

1.51–5.77

0.002

 ≤ 4

73(57.9)

13(19.2)

1[Reference]

LVSI

 Pos

93(73.8)

31(39.8)

1.86

0.73–4.75

0.196

 Neg

33(26.2)

7(21.2)

1[Reference]

Nerve invasion

 Pos

17(13.5)

7(41.2)

1.76

0.62–5.04

0.291

 Neg

109(86.5)

31(28.4)

1[Reference]

Histological type

 SCC

106(84.1)

31(29.2)

1.30

0.48–3.58

0.608

 Non-SCC

20(15.9)

7(35.0)

1[Reference]