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Fig. 2 | BMC Women's Health

Fig. 2

From: Fanconi anemia complementation group D2 promotes sensitivity of endometrial cancer cells to chemotherapeutic agents by inhibiting the ferroptosis pathway

Fig. 2

Fancd2 was up-regulated in Ishikawa/TAX cells and associated with paclitaxel resistance. A Fancd2 mRNA expression levels in Ishikawa cells and Ishikawa/TAX cells were assessed by RT-qPCR. B Western blot was used to detect Fancd2 protein expression levels in Ishikawa cells and Ishikawa/TAX cells. C MTT assay was applied to test the cellular activity of Ishikawa cells and Ishikawa/TAX cells under paclitaxel treatment. D Clonal formation assay was utilized to determine the number of cell clones in Ishikawa cells and Ishikawa-TAX cells. E Flow cytometry was employed to detect apoptosis in Ishikawa cells and Ishikawa-TAX cells. ** P < 0.01

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BMC Women's Health

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