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Fig. 4 | BMC Women's Health

Fig. 4

From: Fanconi anemia complementation group D2 promotes sensitivity of endometrial cancer cells to chemotherapeutic agents by inhibiting the ferroptosis pathway

Fig. 4

Knock-down of Fancd2 promoted ferroptosis in Ishikawa/TAX cells. A RT-qPCR was used to detect the expression level of Fancd2 in Ishikawa/TAX cells. B MTT assay was adopted to assess the cell viability of Ishikawa/TAX cells under paclitaxel treatment, and IC50 was calculated. C Clonal formation assay was employed to examine the number of cell clones in the siNC group, si-Fancd2 group, Fer-1 group and si-Fancd2 + Fer-1 group. D Flow cytometry was utilized for evaluating the apoptosis level in the siNC group, si-Fancd2 group, Fer-1 group, and si-Fancd2 + Fer-1 group. ** P < 0.01 vs. siNC; ## P < 0.01 vs. si-Fancd2; $$ P < 0.01, vs. Fer-1

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BMC Women's Health

ISSN: 1472-6874

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