Skip to main content

Table 5 Association of genotypes with serum minerals in the control participants (N = 183)

From: Micronutrients intake and genetic variants associated with premature ovarian insufficiency; MASHAD cohort study

Polymorphism

Zinc

P-value

Copper

P-value

Phosphate

P-value

Calcium

P-value

Vitamin D

P-value

Magnesium

P-value

rs4806660

TT

82.63 ± 1.7

NS

98.7 ± 3.6a

0.010

4.5 ± 0.2

NS

9.5 ± 0.3

NS

12.85 ± 2.5

NS

1.08 ± 0.07

NS

TC

84.82 ± 1.8

112.19 ± 3.5b

4.7 ± 0.2

9.7 ± 0.1

9.48 ± 2.3

1.08 ± 0.03

CC

88.23 ± 3.6

127.6 ± 23.8ab

4.5 ± 0.2

9.3 ± 0.2

10.45 ± 2.1

1.07 ± 0.03

rs451417

CC

84.4 ± 1.9

NS

110.4 ± 3.3

NS

4.8 ± 0.1

NS

9.6 ± 0.2

NS

12.6 ± 3.1

NS

1.07 ± 0.03

NS

CA

83.7 ± 1.8

104.9 ± 4.6

4.4 ± 0.3

9.9 ± 0.6

10.2 ± 1.7

1.09 ± 0.09

AA

81.8 ± 3.2

93.5 ± 7.9

4.4 ± 0.5

8.7 ± 0.7

11.2 ± 4.7

1.06 ± 0.06

rs16991615

GG

83.9 ± 1.9

NS

102.06 ± 4.1

NS

4.69 ± 0.23

NS

9.5 ± 0.2

NS

23.2 ± 4.4

NS

1.09 ± 0.03

NS

GA

83.8 ± 1.6

109.9 ± 3.6

4.61 ± 0.34

9.8 ± 0.5

13.7 ± 4.8

1.06 ± 0.08

AA

83.9 ± 4.5

109.2 ± 9.6

4.67 ± 0.21

9.6 ± 0.3

17.35 ± 4.1

1.13 ± 0.03

rs7246479

TT

82.6 ± 1.8

NS

98.7 ± 3.6a

0.010

4.3 ± 0.3

NS

9.6 ± 0.2

NS

10.2 ± 2.2

NS

1.08 ± 0.03

NS

TA

84.8 ± 1.8

112.1 ± 3.5

4.5 ± 0.2

9.5 ± 0.4

12.8 ± 2.5

1.08 ± 0.07

AA

88.2 ± 3.6

127.6 ± 23.8a

4.7 ± 0.2

9.7 ± 0.1

9.4 ± 2.3

1.02 ± 0.04

rs244715

AA

84.1 ± 1.5

NS

102.8 ± 3.1

NS

4.5 ± 0.3

NS

9.5 ± 0.4

NS

10.6 ± 1.7

NS

1.09 ± 0.8

NS

AG

84.4 ± 2.3

112.5 ± 4.9

4.9 ± 0.2

9.7 ± 0.2

14.3 ± 4.7

1.07 ± 0.03

GG

74.4 ± 1.5

118.5 ± 14.4

4.4 ± 0.3

9.6 ± 0.2

12.2 ± 3.6

1.06 ± 0.07

rs1046089

GG

82.5 ± 1.7

NS

103.3 ± 3.9b

0.010

4.3 ± 0.2

NS

9.5 ± 0.4

NS

12.2 ± 2.3

NS

1.05 ± 0.2

NS

GA

83.8 ± 1.9

103.9 ± 3.6a

4.3 ± 0.4

9,6 ± 0.8

13.5 ± 2.8

1.1 ± 0.1

AA

89.4 ± 3.2

128 ± 8.4ab

4.7 ± 0.1

9.6 ± 0.1

10.7 ± 2.6

1.07 ± 0.03

rs2303369

CC

82.9 ± 1.7

NS

105.5 ± 3.9b

0.010

4.2 ± 0.4

NS

9.6 ± 0.7

NS

12.2 ± 2.7

NS

1.2 ± 0.1

NS

CT

84.1 ± 1.9

102.8 ± 3.7a

4.3 ± 0.4

9.5 ± 0.8

13.5 ± 2.8

1.1 ± 0.1

TT

87.7 ± 2.6

135.1 ± 9.2ab

4.7 ± 0.1

9.6 ± 0.1

10.7 ± 2.6

1.07 ± 0.03

rs10183486

CC

82.8 ± 1.8

NS

109.1 ± 4.3

NS

4.7 ± 0.23

NS

9.6 ± 0.19

NS

10.4 ± 2.3

NS

1.08 ± 0.03

NS

CT

84.1 ± 1.7

103.2 ± 3.4

4.6 ± 0.2

9.6 ± 0.47

12.6 ± 2.8

1.08 ± 0.04

TT

90.3 ± 5.01

106.1 ± 1.6

4.5 ± 0.23

9.5 ± 0.3

12.2 ± 2.2

1.07 ± 0.07

  1. One-way Analysis of Variance (ANOVA) and Tukey tests were applied; Data are represented as Mean ± SD (Standard Deviation); All data regarding the concentrations of all micronutrients had normal distribution. a,b & c:same letters show significant differences between genotypes
Back to article page

BMC Women's Health

ISSN: 1472-6874

Contact us