Table 2 Multivariable models of OS and PFS adjusted to prognostic factors

PBLC (prior to ICIs)

0.280(0.095–0.823)

0.021

0.413(0.141–1.213)

0.108

Adjusted PBLC (prior to ICIs)

0.482(0.233–0.999)

0.049

0.693(0.337–1.426)

0.319

PBLC (post treatment)

0.459(0.148–1.422)

0.177

0.791(0.285–2.422)

0.681

NLR

1.150(1.052–1.257)

0.002

1.086(1.002–1.177)

0.045

Adjusted NLR

2.575(1.217–5.447)

0.013

2.189(1.085–4.414)

0.029

MLR

3.880(0.665–22.626)

0.132

3.433(0.610-19.327)

0.162

Adjusted MLR

1.802(0.858–3.787)

0.120

1.619(0.802–3.271)

0.179

PLR

1.004(1.000-1.008)

0.028

1.002(0.999–1.006)

0.161

Adjusted PLR

1.596(0.714–3.568)

0.255

1.596(0.709–3.593)

0.259

ICIs lines

1.929(1.289–2.887)

0.001

2.778(1.819–4.241)

0.00

Age

1.007(0.959–1.057)

0.784

1.075(1.011–1.143)

0.021