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Fig. 3 | BMC Women's Health

Fig. 3

From: PHLPP1 inhibits the growth and aerobic glycolysis activity of human ovarian granular cells through inactivating AKT pathway

Fig. 3

Knockdown of PHLPP1 ameliorated the DHT-induced damage of KGN cells. A, B PHLPP1 was successfully silenced. C Proliferation of DHT-treated cells was significantly promoted by knockdown of PHLPP1. D, E Silencing PHLPP1 inhibited apoptosis of DHT-treated KGN cells. F Silencing PHLPP1 promoted glycolysis in DHT-treated KGN cells. G ROS production in DHT-treated cells was suppressed by knockdown of PHLPP1. * p < 0.05, *** p < 0.001 vs. Vehicle or shNC. !!! p < 0.001 vs. DHT + shNC

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BMC Women's Health

ISSN: 1472-6874

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