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Fig. 4 | BMC Women's Health

Fig. 4

From: PHLPP1 inhibits the growth and aerobic glycolysis activity of human ovarian granular cells through inactivating AKT pathway

Fig. 4

Inhibiting AKT rescued the function of PHLPP1 silencing in DHT-treated KGN cells. A, B Protein levels of AKT and p-AKT. B. AKT inhibitor MK-2206 abolished DHT-induced proliferation suppression in shPHLPP1-silencing KGN cells. C MK-2206 inhibited the glycolysis activity in DHT-treated PHLPP1-silencing KGN cells. D Levels of AKT and p-AKT. ** p < 0.01, *** p < 0.001 vs. Vehicle; !! p < 0.01, !!! p < 0.001 vs. DHT + shNC + Vehicle; ### p < 0.001 vs. DHT + shPHLPP1-1 + Vehicle

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BMC Women's Health

ISSN: 1472-6874

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