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Fig. 5 | BMC Women's Health

Fig. 5

From: PHLPP1 inhibits the growth and aerobic glycolysis activity of human ovarian granular cells through inactivating AKT pathway

Fig. 5

AKT activator SC79 disrupted the function of PHLPP1 overexpression. A, B PHLPP1 was successfully overexpressed. C SC79 promoted the proliferation of PHLPP1-overexpressing KGN cells. D SC79 promoted glycolysis of PHLPP1-overexpressing KGN cells. E Expression of AKT and p-AKT. F Schematic diagram of the mechanism by which PHLPP1 inhibits the growth and glycolysis of human ovarian granular cells through inactivating AKT pathway. ** p < 0.01, *** p < 0.001 vs. oeNC; !!! p < 0.001 vs. oePHLPP1 + Vehicle

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BMC Women's Health

ISSN: 1472-6874

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