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Fig. 1 | BMC Women's Health

Fig. 1

From: The causal effect of reproductive factors on pelvic floor dysfunction: a Mendelian randomization study

Fig. 1

Schematic representation of TSMR and MVMR. (A) Schematic representation of TSMR. MR is based on three key assumptions: first, there is a significant association between genetic variation and exposure; second, there is no correlation between the IV and any confounding factors; and third, IV is associated with FGP and SUI (outcome) only through reproductive factors (exposure) and not through direct association. (B) Schematic representation of MVMR

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