Table 2 The comparison of maternal outcomes between synbiotic-supplemented and placebo groups

Duration of pregnancy (days)^*

232.00 (20.78)

232.60 (21.20)

-1.99 (-9.88 to 5.89)

0.618^†

0.87

Time from PE diagnosis to delivery (days)^*

21.59 (24.03)

19.21 (17.29)

3.34 (-4.50 to 11.95)

0.40^†

0.30

Systolic blood pressure^*

pre-intervention

134.07 (9.08)

134.67 (8.81)

0.59 (-2.53 to 3.72)

0.708^±

-

post-intervention

138.15 (25.85)

153.64 (22.86)

-13.54 (-22.07 to -5.01)

0.002^†

0.004

Diastolic blood pressure^*

pre-intervention

83.12 (7.37)

83.34 (5.10)

0.21 (-2.00 to 2.44)

0.846^±

-

post-intervention

83.23 (18.12)

95.01 (12.45)

-10.30 (-15.90 to -4.70)

> 0.001^†

0.001

N (%)

N (%)

Adjusted odds ratio (95% CI)

p-value^*

Incidence of severe preeclampsia^**

28 (43.8)

49 (76.6)

5.01 (2.04 to 12.29)

> 0.001^‡

0.001

Premature rupture of membranes^**

9 (14.1)

4 (6.3)

0.31 (0.79 to 1.21)

0.093^‡

0.112

Vaginal delivery^**

33 (36.19)

32 (25.78)

0.95 (0.37 to 2.40)

0.920^‡

0.26

Incidence of serious complications (cerebral stroke, renal failure, HELLP syndrome, DIC, pulmonary edema)^**

7 (11.9)

4 (6.3)

1.48 (0.30 to 7.24)

0.627^‡

0.206

Use of antihypertensive drugs^**

53 (82.8)

59 (92.2)

1.44 (0.43 to 4.82)

0.553^‡

0.573