Table 3 The comparison of some biochemical factors before and after the intervention between synbiotic and placebo groups
Biochemical factors | Synbiotic (n = 64) Mean (SD) | Placebo (n = 64) Mean (SD) | Adjusted mean difference (95% CI) | p-value§ | p-value£ | |
|---|---|---|---|---|---|---|
Platelet count (count/ml) | Pre-intervention | 211265.62 (55177.41) | 212421.87 (64776.49) | 1156.25 (-19892.91 to 22205.41) | 0.914†| - |
Post-intervention | 185,785 (7004) | 190,789 (6943) | -5004.56 (-25533.69 to 15524.55) | 0.630‡‘± | 0.391£ | |
Creatinine (mg/dL) | Pre-intervention | 0.82 (0.16) | 0.80 (0.12) | -0.02 ()-0.07 to 0.02 | 0.350†| - |
Post-intervention | 0.79 (0.01) | 0.86 (0.01) | -0.06 (-0.11 to -0.02) | 0.005‡‘± | 0.033£ | |
LDH (u/L) | Pre-intervention | 385.29 (99.84) | 370.98 (94.23) | -14.31 (-50.88 to 22.25) | 0.439†| - |
Post-intervention | 441.50 (17.99) | 405.9 (18.17) | 35.51 (-17.73 to 88.76) | 0.189‡‘± | 0.245£ | |
Random proteinuria (mg) | Pre-intervention | 2.07 (1.23) | 2.10 (1.00) | 0.30 (-0.36 to 0.42) | 0.881†| - |
Post-intervention | 1.64 (1.22) | 1.92 (1.07) | -0.47 (-0.92 to 0.01) | 0.044‡‘± | 0.067£ | |
ALT (u/L) | Pre-intervention | 19.51 (12.67) | 15.76 (11.22) | -2.47 (6.73 to 1.77) | 0.252†| - |
Post-intervention | 22.70 (22.72) | 15.57 (9.80) | 4.91 (-3.07 to 12.91) | 0.225‡‘± | 0.212£ | |
AST (u/L) | Pre-intervention | 20.34 (10.26) | 19.02 (6.81) | -0.38 (-3.78 to 3.02) | 0.824†| - |
Post-intervention | 23.29 (14.24) | 20.95 (16.92) | 1.27 (-5/68 to 8.22) | 0.717‡‘± | 0.987£ | |