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Table 2 Treatment details for women with advanced stage ovarian cancer stratified by age, N (%)

From: Disparities in treatment modalities and survival among older patients with high-grade serous ovarian cancer

  

Age group (Age at diagnosis, years)

p-Value

Characteristics

Total (n = 3584)

65–74 (n = 2296)

≥ 75 (n = 1288)

Stage

   

0.921

 IIIC

 IV

2127(59.3)

1457(40.7)

1364(59.4)

932(40.6)

763(59.2)

525(40.8)

 

LND

   

< 0.001

 Non-LN

 1–9 LNs

 10–19 LNs

 ≥ 20 LNs

 Unknown

1963(54.8)

841(23.5)

378(10.5)

318(8.9)

163(2.3)

1197(52.1)

555(24.2)

255(11.1)

236(10.3)

53(2.3)

766(59.5)

286(22.2)

123(9.5)

82(6.4)

31(2.4)

 

Surgery method

   

< 0.001

 No surgery

 USO/BSO ± Hys

 USO/

 BSO&Ome ± Hys

363(10.1)

290(8.1)

587(16.4)

157(6.8)

172(7.5)

377(16.4)

206(16.0)

118(9.2)

210(16.3)

 

 Debulking

 Pelvic

 exenteration

2250(62.8)

94(2.6)

1519(66.2)

71(3.1)

731(56.8)

23(1.8)

 

Treatment type

   

< 0.001

 Chemo + surgery

 Surgery

 Chemo

 No chemo

 or surgery

2860(79.8)

361(10.1)

261(7.3)

126(2.8)

1951(85.0)

188(8.2)

124(5.4)

33(1.4)

909(70.6)

173(13.4)

137(10.6)

69(5.4)

 

NACT

   

0.212

 No

 Yes

1801(63.0)

1059(37.0)

1244(63.8)

707(36.2)

557(61.3)

352(38.7)

 

Residual disease

   

< 0.001

 PDS/Optimal

 IDS/ Optimal

 PDS/Suboptimal

 IDS/Suboptimal

 No surgery

 Unknown

1184(33.0)

592(16.5)

421(11.7)

237(6.7)

363(10.1)

787(22.0)

803(35.0)

407(17.7)

275(12.0)

151(6.6)

157(6.8)

503(21.9)

381(29.6)

185(14.4)

146(11.3)

86(6.7)

206(16.0)

284(22.0)

 
  1. LNs, lymph nodes; LND, lymphadenectomy; USO, unilateral oophoro-salpingectomy; BSO, bilateral oophoro-salpingectomy; Hys, hysterectomy; Ome, omentectomy; NACT: neoadjuvant-chemotherapy; PDS, primary debulking surgery; IDS, interval debulking surgery.