Table 2 Gut Microbiome, Diet, and Psychosocial Stress Variables by Race

Top 25 Genera

AA(N = 29)

Mean ± SD

EA(N = 31)

Mean ± SD

p-value

AA

Median

EA

Median

p-value

Alpha Diversity (ASV)

95.73 ± 27.52

113.48 ± 32.29

0.032†

98.5

107

0.063

PD Whole tree

9.226 ± 2.515

10.649 ± 3.079

0.068

9.039

10.016

0.121

Shannon

4.984 ± 0.782

5.135 ± 0.498

0.392

5.065

5.063

0.649

Simpson

0.931 ± 0.058

0.942 ± 0.024

0.359

0.954

0.941

0.987

Bacteroides

0.233 ± 0.143

0.239 ± 0.128

0.877

0.201

0.238

0.736

Blautia

0.118 ± 0.065

0.162 ± 0.081

0.030

0.110

0.158

0.035

Faecalibacterium

0.095 ± 0.068

0.090 ± 0.061

0.808

0.091

0.080

0.946

Agathobacter

0.031 ± 0.034

0.038 ± 0.051

0.564

0.022

0.023

0.973

Fusicatenibacter

0.033 ± 0.026

0.030 ± 0.019

0.609

0.027

0.034

0.859

Subdoligranulum

0.026 ± 0.020

0.028 ± 0.023

0.736

0.024

0.028

0.893

Akkermansia

0.019 ± 0.035

0.016 ± 0.034

0.768

0.000

0.002

0.480

Ruminococcus 2

0.014 ± 0.018

0.017 ± 0.018

0.395

0.000

0.015

0.220

Anaerostipes

0.017 ± 0.015

0.018 ± 0.016

0.937

0.015

0.014

0.893

Ruminococcus 1

0.015 ± 0.021

0.017 ± 0.020

0.719

0.005

0.009

0.665

Ruminococcus_torques

0.016 ± 0.015

0.016 ± 0.013

0.931

0.010

0.014

0.800

Roseburia

0.015 ± 0.022

0.015 ± 0.012

0.901

0.008

0.014

0.206

Eubacterium_hallii

0.013 ± 0.010

0.015 ± 0.009

0.391

0.012

0.012

0.409

Romboustia

0.014 ± 0.017

0.014 ± 0.018

0.960

0.008

0.005

0.912

Alistipes

0.015 ± 0.014

0.010 ± 0.008

0.111†

0.013

0.008

0.288

Bifidobacterium

0.020 ± 0.033

0.006 ± 0.008

0.037†

0.003

0.002

0.402

Dorea

0.011 ± 0.009

0.010 ± 0.006

0.441

0.009

0.008

0.906

Rumin 002

0.012 ± 0.015

0.008 ± 0.009

0.189†

0.006

0.005

0.466

Lachno NK4A136

0.005 ± 0.006

0.010 ± 0.014

0.088†

0.003

0.004

0.261

Lactobacillus

0.004 ± 0.012

0.001 ± 0.003

0.163†

0.000

0.000

0.172

Streptococcus

0.009 ± 0.013

0.007 ± 0.011

0.501

0.004

0.003

0.417

Clostridium_sensu

0.009 ± 0.017

0.006 ± 0.011

0.399

0.003

0.001

0.138

Ruminococcus_gauvreauii

0.006 ± 0.007

0.008 ± 0.010

0.323

0.004

0.006

0.708

Eubacterium coprostanoli

0.007 ± 0.009

0.006 ± 0.007

0.839

0.004

0.004

0.932

Escherischia Shigella

0.007 ± 0.018

0.007 ± 0.017

0.959

0.000

0.001

0.835

Dietary Variables

AA

EA

p -value

AA

EA

p -value

Dietary Inflammation Score (DIS)

0.79 ± 2.27

−0.931 ± 2.55

0.010

0.55

−1.32

0.004

Healthy Eating Index (HEI) Score

62.3 ± 11

69.3 ± 11.2

0.021

59.9

70.8

0.014

Cal:EER ratio

0.90 ± 0.37

0.93 ± 0.36

0.750

0.81

0.88

0.575

Percent Carb

52 ± 9

47 ± 10

0.054

48

46

0.049

Percent Fat

34 ± 5

37 ± 8

0.082

34

36

0.089

Percent Protein

15 ± 4.5

16 ± 3

0.156

15

17

0.095

Fiber (g)

19.6 ± 9.1

28.5 ± 16.4

0.015

17.7

26.7

0.014

Beta Carotene (mcg)

5401 ± 8308

9468 ± 10,838

0.119

2378

6027

0.012

Alpha Carotene (mcg)

456 ± 499

1779 ± 2631

0.012†

249

700

0.008

Vitamin C (mg)

147 ± 115

173 ± 187

0.540

114

136

0.453

Vitamin D (IU)

264 ± 200

259 ± 134

0.914

219

260

0.412

Vitamin E (IU)

16.8 ± 9.2

25 ± 17.4

0.030

13.5

21.6

0.025

Omega 6:3

8.2 ± 1.9

9.3 ± 2.6

0.086

8.5

8.7

0.236

Added Sugar (tsp)

21.3 ± 17.6

13.6 ± 15.2

0.083

15.5

10.5

0.074

Sweet Servings

3 ± 3

1.5 ± 2.2

0.031†

1.8

0.66

0.010

Fruit Servings

0.88 ± 1.1

1.8 ± 1.5

0.012†

0.50

2

0.006

Vegetable Servings

1.3 ± 1.8

2.1 ± 1.9

0.098

0.50

2

0.026

Fried Food Servings

0.50 ± 0.40

0.24 ± 0.27

0.015

0.31

0.15

0.003

Psychosocial Stress Variables

AA

EA

p -value

AA

EA

p -value

Hair Cortisol (HC)

0.113 ± 0.227

0.035 ± 0.033

0.080†

0.043

0.024

0.008

Saliva Cortisol (SC)

0.224 ± 0.144

0.173 ± 0.101

0.121

0.182

0.158

0.185

Recent Discrimination (RED)

10.8 ± 5.8

8.4 ± 6.1

0.174

10.5

6.5

0.103

Lifetime Discrimination (LED)

9.5 ± 4

6.7 ± 3.5

0.014

9.5

6

0.011

Perceived Stress Score (PSS)

20 ± 6.5

15.2 ± 6.8

0.007

20

13

0.008

Depression (PHQ-8)

7 ± 5.4

6 ± 5.3

0.544

5

5

0.423