Fig. 3

A 52-year-old woman with 44-mm HR⁺/HER2⁻ subtype in the lower central quadrant of the left breast. Before NAC, A a CC image of mammography revealed a 62-mm extent of segmental distribution of microcalcifications. After NAC, B the size, mass, and extent of microcalcifications did not decrease on mammography. On C a computer-aided detection (CAD) image from MRI, a 44-mm, irregularly shaped, non-mass-like enhancement was noted. After NAC, D the CAD image from MRI revealed that the enhancement had decreased to a 35-mm extent. She underwent total mastectomy, and the pathology showed a residual DCIS of 42 mm