Table 6 Univariate and multivariate analyses of death

Age at diagnosis, years (ref =  < 40)

  ≥ 40

0.788 (0.380- 1.730)

0.534

Clinical T stage before NAC (ref = cT1)

 cT2-4

1.345 (0.250- 25.040)

0.780

Clinical N stage before NAC (ref = cT0)

 cN1-3

0.727 (0.230- 3.230)

0.625

Lymphovascular invasion (ref = absent)

 Present

7.096 (3.380- 16.050)

 < 0.001

5.230 (2.190- 13.620)

 < 0.001

HR + (ref = negative)

 Positive

0.482 (0.230 -0.960)

0.041

0.420 (0.150- 1.110)

0.082

HER2⁺(ref = negative)

 Positive

0.436 (0.200- 0.910)

0.031

0.320 (0.120- 0.780)

0.015

Ki-67 before NAC (ref =  < 14%)

  ≥ 14%

1.672 (0.560- 7.190)

0.413

Ki-67 after NAC (ref =  < 14%)

  ≥ 14%

4.167 (1.870- 10.270)

0.001

4.030 (1.480- 12.090)

0.009

Radiologic response of MRI (ref = CR)

 Non-CR

12.741 (2.680- 228.220)

0.013

N/A

0.988

Extent of surgery (ref = total mastectomy)

 Partial mastectomy

0.613 (0.300- 1.220)

0.169

Pre-NAC extent of microcalcifications, mm (ref =  < 10)

  ≥ 10

0.433 (0.100- 2.990)

0.309

Post-NAC extent of microcalcifications, mm (ref =  < 10)

  ≥ 10

0.533 (0.130- 3.620)

0.436

Residual microcalcification (ref = absent)

 Present

0.869 (0.248–2.351)

0.801

1.670 (0.400–6.010)

0.447