Table 5 Diagnostic value of plasma exosomal miR-223 and CA125 for EOC patients at early-stage relative to healthy controls
From: Diagnostic value of plasma-derived exosomal miR-223 for epithelial ovarian cancer
cutoff value | AUC (95% CI) | sensitivity | specificity | Youden index | |
|---|---|---|---|---|---|
Plasma CA125 | 34.85 U/mL | 0.928 (0.875–0.981) | 94.9% | 84.6% | 0.795 |
Plasma exosomal miR-223 | 1.345 | 0.778 (0.683–0.873) | 76.9% | 73.1% | 0.500 |
Combination | - | 0.944 (0.899–0.990) | 97.4% | 88.5% | 0.859 |