Table 1 Participant characteristics

Number of women, n (%)

588

51 (8.7)

537 (91)

117 (20)

471 (80)

166 (28)

422 (72)

73 (12)

515 (88)

62 (10)

526 (89)

145 (25)

443 (75)

Age at diagnosis, mean

57.5

67.3

56.6

65.5

55.5

62.8

55.4

65.0

56.5

64.6

56.7

64.1

55.3

Urban/rural, n (%)

 Urban

286 (49)

29 (57)

257 (48)

46 (39)

240 (51)

76 (46)

210 (50)

36 (49)

250 (48)

28 (45)

258 (49)

65 (45)

221 (50)

 Less urban

143 (24)

11 (22)

132 (25)

31 (26)

112 (24)

38 (23)

105 (25)

17 (23)

126 (24)

14 (23)

129 (24)

34 (23)

109 (25)

 Rural

159 (27)

11 (22)

148 (27)

40 (34)

119 (25)

52 (31)

107 (25)

20 (27)

139 (27)

20 (32)

139 (26)

46 (32)

113 (25)

Tumor histology, n (%)

 Serous

365 (62)

35 (69)

330 (61)

80 (68)

285 (60)

120 (72)

245 (58)

52 (71)

313 (61)

42 (68)

323 (61)

102 (70)

263 (59)

 Mucinous

23 (4)

1 (2.0)

22 (4.1)

3 (2.6)

20 (4.2)

6 (3.6)

17 (4.0)

3 (4.1)

20 (3.9)

2 (3.2)

21 (4.0)

4 (2.8)

19 (4.3)

 Endometrioid

58 (10)

1 (2.0)

57 (11)

5 (4.3)

53 (11)

8 (4.8)

50 (12)

3 (4.1)

55 (11)

-

58 (11)

11 (7.6)

47 (11)

 Other

142 (24)

14 (27)

128 (24)

29 (25)

113 (24)

32 (19)

110 (26)

15 (20)

127 (25)

18 (29)

124 (24)

28 (19)

114 (26)

Stage at diagnosis, n (%)

 I

143 (24)

13 (25)

130 (24)

25 (21)

118 (25)

37 (22)

106 (25)

19 (26)

124 (24)

18 (29)

125 (24)

32 (22)

111 (25)

 II

48 (8.2)

2 (3.9)

46 (8.6)

6 (5.1)

42 (8.9)

8 (4.8)

40 (9.5)

5 (6.8)

43 (8.3)

7 (11)

41 (7.8)

7 (4.8)

41 (9.3)

 III

279 (47)

24 (47)

255 (47)

62 (53)

217 (46)

93 (56)

186 (44)

33 (45)

246 (48)

28 (45)

251 (48)

73 (50)

206 (46)

 IV

98 (17)

11 (22)

87 (16)

17 (14)

81 (17)

21 (13)

77 (18)

13 (18)

85 (16)

8 (13)

90 (17)

26 (18)

72 (16)

Unknown

20 (3.4)

1 (2.0)

19 (3.5)

7 (6.0)

13 {2.8}

7 (4.2)

13 (3.1)

3 (4.1)

17 (3.3)

1 (1.6)

19 (3.6)

7 (4.8)

13 (2.9)

Surgery, n (%)

498 (85)

40 (78)

458 (85)

95 (81)

403 (85)

132 (79)

366 (87)

64 (88)

434 (84)

51 (82)

447 (85)

127 (88)

371 (84)

Chemotherapy, n (%)

516 (88)

45 (88)

471 (88)

100 (85)

416 (88)

149 (90)

367 (87)

58 (79)

458 (89)

52 (84)

464 (88)

127 (88)

389 (88)

Comorbidities ^a

 Hypertension, n (%)

248 (42)

47 (92)

201 (37)

98 (84)

150 (32)

138 (83)

110 (26)

63 (86)

185 (36)

57 (92)

191 (36)

122 (84)

126 (28)

 CVD^b, n (%)

294 (50)

47 (92)

247 (46)

103 (88)

191 (40)

143 (86)

151 (36)

64 (88)

230 (45)

58 (93)

236 (45)

125 (86)

169 (38)

 Diabetes, n (%)

36 (6.1)

7 (14)

29 (5.4)

13 (11)

23 (4.9)

18 (11)

18 (4.3)

12 (16)

24 (4.7)

7 (11)

29 (5.5)

11 (7.6)

25 (5.6)

CCI ^c, n (%)

 0

395 (67)

15 (29)

380 (71)

56 (48)

339 (72)

88 (53)

307 (73)

31 (42)

364 (71)

25 (40)

370 (70)

76 (52)

319 (72)

 1

54 (9.2)

7 (14)

47 (8.7)

11 (9.4)

43 (9.1)

13 (7.8)

41 (9.7)

10 (14)

44 (8.5)

5 (8.1)

49 (9.3)

16 (11)

38 (8.6)

 2

71 (12)

21 (41)

50 (9.3)

34 (29)

37 (7.9)

41 (24.7)

30 (7.1)

17 (23)

54 (10)

21 (34)

50 (9.5)

32 (22)

39 (8.8)

 3+

68 (12)

8 (16)

60 (11)

16 (14)

52 (11)

24 (14)

44 (10)

15 (20)

53 (10)

11 (18)

57 (11)

21 (14)

47 (11)

Use of other medications ^a

 Statins, n (%)

19 (3.2)

8 (15.7)

11 (2.0)

8 (6.8)

11 (2.3)

14 (8.4)

5 (1.2)

1 (1.4)

18 (3.5)

6 (9.7)

13 (2.5)

10 (6.9)

9 (2.0)

 Metformin, n (%)

27 (4.6)

6 (11.8)

21 (3.9)

14 (12)

13 (2.8)

17 (10)

10 (2.4)

8 (11)

19 (3.7)

7 (11)

20 (3.8)

10 (6.9)

17 (3.8)

 Insulin, n (%)

5 (0.8)

2 (3.9)

3 (0.6)

-

5 (1.1)

2 (1.2)

3 (0.7)

2 (2.7)

3 (0.6)

-

5 (0.9)

1 (0.7)

4 (0.9)

 Anticoagulants, n (%)

13 (2.2)

5 (9.8)

8 (1.5)

8 (6.8)

5 (1.1)

8 (4.8)

5 (1.2)

4 (5.5)

9 (1.8)

3 (4.8)

10 (1.9)

8 (5.5)

5 (1.1)