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Table 3 Univariate and multivariate analyses of the prognostic factors for overall survival in EC

From: Association of tet methylcytosine dioxygenase 2 and 5-hydroxymethylcytosine in endometrioid adenocarcinoma and its clinical significance

 

Univariate analysis

Multivariate analysis

 

HR

P value

95%CI

HR

P value

95%CI

TET2 and 5hmC level

 T+5+ vs T+5vs T5+ vs T5

3.035

< 0.001*

1.751–5.259

2.843

0.007*

1.226–3.605

Age (year)

 

0.989

0.986

0.308–3.181

   

Menopausal status

 Pre-vs Post-menopause

1.056

0.835

0.634–1.759

   

Differentiation

 Well vs Moderate vs Poor

1.812

0.036*

1.040–3.157

   

Myometrial invasion

 < 1/2 vs ≥ 1/2

0.955

0.868

0.551–1.653

   

Lymph node metastasis

 Negative vs Positive

5.828

0.015*

1.329–14.615

5.241

0.037*

1.169–13.856

FIGO Stage

 I vs II vs III

4.261

0.006*

2.347–7.154

3.979

0.023*

2.153–6.780

  1. HR Hazard ratio, CI Confidence interval
  2. *P < 0.05