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Table 4 The interaction between GRS with CSI (378) and N6/N3 (279) on psychological disorders in obese and overweight women

From: Investigation of the interaction between Genetic Risk Score (GRS) and fatty acid quality indices on mental health among overweight and obese women

Variable

GRS

CSI

T1

T2

T3

Crude

Model 1

Crude

Model 1

 

B

CI

P

B

CI

P

B

CI

P

B

CI

P

Stress

Reference

0.51

-0.43, 1.45

0.290

0.76

-0.24, 1.77

0.137

-0.16

-1.26, 0.93

0.766

-0.11

-1.29, 1.06

0.851

Anxiety

Reference

-0.03

-0.76, 0.70

0.936

0.16

-0.60, 0.92

0.678

-0.44

-1.30, 0.40

0.305

-0.73

-1.62, 0.16

0.108

Depression

Reference

-0.13

-1.01, 0.75

0.769

0.14

-0.75, 1.05

0.750

-0.66

-1.69, 0.36

0.207

-0.76

-1.81, 0.29

0.159

Dass-21

Reference

0.34

-1.86, 2.55

0.758

1.07

-1.23, 3.38

0.361

-1.27

-3.84, 1.29

0.331

-1.60

-4.30, 1.09

0.244

Variable

GRS

N6/N3

T1

T2

T3

Crude

Model 1

Crude

Model 1

 

B

CI

P

B

CI

P

B

CI

P

B

CI

P

Stress

Reference

0.50

-0.51, 1.52

0.336

0.18

-0.92, 1.29

0.745

0.64

-0.37, 1.66

0.218

0.25

-0.86, 1.36

0.661

Anxiety

Reference

0.49

-0.28, 1.26

0.211

0.41

-0.41, 1.24

0.332

0.79

0.02, 1.57

0.044

0.91

0.08, 1.75

0.031

Depression

Reference

0.70

-0.23, 1.64

0.141

0.48

-0.50, 1.46

0.335

1.08

0.14, 2.02

0.023

1.05

0.06, 2.04

0.037

Dass-21

Reference

1.69

-0.65, 4.05

0.157

1.07

-1.44, 3.60

0.402

2.52

0.17, 4.88

0.036

2.22

-0.31, 4.75

0.086

  1. CI: confidence interval; CSI: cholesterol to saturated fat index; GRS: genetic risk scores; T: tertile
  2. GLM was performed to identify the interaction between GRS with CSI and N6/N3 on psychological disorders
  3. model 1 = adjusted for potential confounding factors including (age, energy intake, physical activity and BMI)
  4. a: BMI considered as collinear for body fat percentage and waist circumference, and these variables are adjusted for age, physical activity, and total energy intake
  5. p < 0.1 was considered significant